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Influenza Vaccine - Influenza Vaccine - Merck ... - The Merck Manuals

LAIV efficacy and its impact on vulnerable groups are still debated. This systematic review aims to investigate whether the LAIV is safe and effective in adults, including those with underlying clinical conditions, pregnant women, and children younger than 24 months.

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LAIV was licensed by the Food and Drug Administration (FDA) in June of 2003. The Advisory Committee on Immunization Practices (ACIP) thereafter recommended LAIV as an option for vaccination of...

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Intranasal powder live attenuated influenza vaccine is ... - Nature

Summary of Data Reviewed. Review of LAIV effectiveness data for previous seasons in the United States confirms low to no significant effectiveness of LAIV against influenza A (H1N1)pdm09-like viruses. However, LAIV was generally effective against influenza B viruses and was of similar effectiveness to IIV against influenza A (H3N2) viruses.

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